Article
Possible association of rare autosomal folate sensitive fragile sites and idiopathic mental retardation: a blind controlled population study.
Clinical genetics - 1 Oct 1990
Chudley A E, Ray M, Evans J A, Cheang M
Abstract excerpt
The expression of folate sensitive fragile sites (FS) was assessed in cord blood lymphocyte cultures obtained from 790 newborns (NB) and in peripheral blood lymphocyte cultures from 326 institutionalized mentally retarded residents (MR). The mean rate of expression of common FS and the occurrence of rare FS was significantly higher in the MR population. Age, sex and history of chronic medication use did not...
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