Possible association of rare autosomal folate sensitive fragile sites and idiopathic mental retardation: a blind controlled population study.

doi:10.1111/j.1399-0004.1990.tb03577.x

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Article

Possible association of rare autosomal folate sensitive fragile sites and idiopathic mental retardation: a blind controlled population study.

Clinical genetics - 1 Oct 1990

Chudley A E, Ray M, Evans J A, Cheang M

Abstract excerpt

The expression of folate sensitive fragile sites (FS) was assessed in cord blood lymphocyte cultures obtained from 790 newborns (NB) and in peripheral blood lymphocyte cultures from 326 institutionalized mentally retarded residents (MR). The mean rate of expression of common FS and the occurrence...

Topics

Abnormalities, Multiple
Adult
Chromosome Aberrations
Chromosome Disorders
Chromosome Fragile Sites
Chromosome Fragility
Female
Folic Acid
Folic Acid Deficiency
Gene Expression Regulation
Gene Frequency
Genetic Carrier Screening

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Counseling

Genetic Testing

Humans

Infant

Infant, Newborn

Intellectual Disability

Source

Open in PubMed

Identifiers

PMID: 2268971
DOI: 10.1111/j.1399-0004.1990.tb03577.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2268971-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Possible association of rare autosomal folate sensitive fragile sites and idiopathic mental retardation: a blind controlled population study.PMID 2268971Read ↗

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