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Genomic and Epigenomic Instability, Fragile Sites, Schizophrenia and Autism

1 Sept 2010

Abstract excerpt

Increasing evidence links genomic and epigenomic instability, including multiple fragile sites regions to neuropsychiatric diseases including schizophrenia and autism. Cancer is the only other disease associated with multiple fragile site regions, and genome and epigenomic instability is a characteristic of cancer. Research on cancer is far more advanced than research on neuropsychiatric disease; hence, insight...

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PMID: 21358990
DOI: 10.2174/138920210793176001

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