Article
Rapid generation of rice mutants via the dominant negative suppression of the mismatch repair protein OsPMS1.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Sept 2012
Xu Jie, Li Meiru, Chen Lei, Wu Guojiang, Li Hongqing
Abstract excerpt
Mismatch repair (MMR) is a conservative pathway for maintaining the genome integrity of different organisms. Although suppression of MMR has resulted in various mutation phenotypes in Arabidopsis, the use of this strategy for mutation breeding in major crops has not been reported. Here, we overexpressed a truncated version of the OsPMS1 protein in rice; this approach is expected to suppress the rice MMR system...
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