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Article

The intermediate filament protein, vimentin, is a regulator of NOD2 activity.

Gut - 1 May 2013

Stevens Craig, Henderson Paul, Nimmo Elaine R, Soares Dinesh C, Dogan Belgin, Simpson Kenneth W, Barrett Jeffrey C, Wilson David C, Satsangi Jack

Abstract excerpt

OBJECTIVE: Mutations in the nucleotide-binding oligomerisation domain-containing protein 2 (NOD2) gene remain the strongest genetic determinants for Crohn's disease (CD). Having previously identified vimentin as a novel NOD2-interacting protein, the authors aimed to investigate the regulatory eff...

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Source

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Identifiers

PMID: 22684479
DOI: 10.1136/gutjnl-2011-301775
PMCID: PMC4225453

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22684479-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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