Article
Characterization of porcine SKIP gene in skeletal muscle development: polymorphisms, association analysis, expression and regulation of cell growth in C2C12 cells.
Meat science - 1 Dec 2012
Xiong Qi, Chai Jin, Deng Changyan, Jiang Siwen, Liu Yang, Huang Tao, Suo Xiaojun, Zhang Nian, Li Xiaofeng, Yang Qianping, Chen Mingxin, Zheng Rong
Abstract excerpt
Skeletal muscle and kidney-enriched inositol phosphatase (SKIP) was identified as a 5'-inositol phosphatase that hydrolyzes phosphatidylinositol (3,4,5)-triphosphate (PI(3,4,5)P3) to PI(3,4)P2 and negatively regulates insulin-induced phosphatidylinositol 3-kinase signaling in skeletal muscle. In...
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