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Functional SNPs in SYISL promoter significantly affect muscle fiber density and muscle traits in pigs.

Animal genetics - 1 Feb 2024

Lv Wei, Peng Yaxin, Hu Jingjing, Zhu Mingfei, Mao Yangcang, Wang Litong, Wang Guoshui, Xu Zaiyan, Wu Wangjun, Zuo Bo

Abstract excerpt

Our previous studies showed that SYISL is a negative regulator of muscle growth and regeneration in mice, pigs and humans. SYISL knockout resulted in an increase in the density of muscle fibers and muscle growth. However, it is unclear whether there are natural mutations in pig SYNPO2 intron sense-overlapping lncRNA (pSYISL) that affect the expression of pSYISL and muscle growth traits. In this study, three SNPs...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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PMID: 37881102
DOI: 10.1111/age.13370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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