Article
Molecular characterization, expression pattern, and association analysis with carcass traits of the porcine SHIP2 gene.
Molecular and cellular biochemistry - 1 Jan 2012
Xiong Qi, Chai Jin, Deng Changyan, Jiang Siwen, Li Xiaofeng, Suo Xiaojun, Zhang Nian, Yang Qianping, Liu Yang, Zheng Rong, Chen Mingxin
Abstract excerpt
Src homology 2-containing inositol 5-phosphatase 2 (SHIP2) has been identified as 5'-inositol phosphatase that hydrolyzes PI(3,4,5)P(3) to PI(3,4)P(2), which negatively regulates insulin-induced Akt signaling in skeletal muscle. In this study, we obtained a 3,795-bp mRNA sequence of porcine SHIP2 that included the full coding region for a protein of 1,264 amino acids. With the use of comparative mapping, we...
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