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Article

Influence of CYP2B6 and ABCB1 SNPs on nevirapine plasma concentrations in Burundese HIV-positive patients using dried sample spot devices.

British journal of clinical pharmacology - 1 Jul 2012

Calcagno Andrea, D'Avolio Antonio, Simiele Marco, Cusato Jessica, Rostagno Roberto, Libanore Valentina, Baietto Lorena, Siccardi Marco, Bonora Stefano, Di Perri Giovanni

Abstract excerpt

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: • Nevirapine pharmacokinetics are affected by several factors including CYP2B6 single nucleotide polymorphisms (SNPs). These genetic profiles are more common in African patients and they affect the drug clearance being associated with higher trough concen...

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Source

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Identifiers

PMID: 22680342
DOI: 10.1111/j.1365-2125.2012.04163.x
PMCID: PMC3394137

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22680342-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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