Article
Association of methylenetetrahydrofolate reductase gene 677C>T polymorphism with hypertension in older women in a population of Buenos Aires City.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2013
Fridman Osvaldo, Porcile Rafael, Morales Analía V, Gariglio Luis O, Potenzoni Miguel A, Turk Noceto Paula C
Abstract excerpt
We examined the relationship between the 677C >T polymorphism in the MTHFR gene and tHcy in normotensive (NT) and hypertensive (HT) subjects and the influence of sex and age in a cross-sectional study. Smoking habits, history of vascular disease, diabetes, and tHcy were significantly associated with T allele as hypertension risk factors. The T allele was significantly related with higher tHcy in (i) men versus...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Argentina
- Cross-Sectional Studies
- Female
- Homocysteine
- Humans
- Hypertension
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)