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Article

Effect of methylenetetrahydrofolate reductase C677T polymorphism on serum folate but not vitamin B12 levels in patients with H-type hypertension.

Molecular biology reports - 1 Oct 2022

Ma Lijuan, Li Jing, Yuan Yuan, Chen Wenwen, Zhao Jun

Abstract excerpt

BACKGROUND: Hyperhomocysteinemia (HHcy) is a common complication in Chinese hypertensive patients and associated with methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, folate, and vitamin B12 (Vit B12) status. This study evaluated the associations of MTHFR C677T polymorphism, folate, and Vit B12 with H-type hypertension. METHODS AND RESULTS: 887 eligible patients with essential hypertension were...

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PMID: 35951145
DOI: 10.1007/s11033-022-07844-w

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