Article
UGT2B7 genetic polymorphisms are associated with the withdrawal symptoms in methadone maintenance patients.
Pharmacogenomics - 1 Jun 2012
Tian Jia-Ni, Ho Ing-Kang, Tsou Hsiao-Hui, Fang Chiu-Ping, Hsiao Chin-Fu, Chen Chia-Hui, Tan Happy Kuy-Lok, Lin Linen, Wu Chi-Shin, Su Lien-Wen, Huang Chieh-Liang, Yang Yi-Hong, Liu Ming-Lun, Chen Yu-Ting, Liu Shu Chih, Hsu Ya-Ting, Kuo Hsiang-Wei, Liu Chen Ting, Yang Yi-Ting, Chen Andrew Ch, Shih Yu-Huei, Liu Yu-Li
Abstract excerpt
AIM: To test whether the genetic polymorphisms within the gene encoding the UGT2B7 gene may have an impact on methadone treatment. MATERIALS & METHODS: Twelve SNPs in UGT2B7 were selected. 366 methadone maintenance treatment patients in Taiwan were recruited and genotyped. RESULTS: In a genotype recessive model, rs6600879, rs6600880, rs4554144, rs11940316, rs7438135, , , , and...
