Article
Immunohistochemical phenotyping of the inflammatory infiltrate in de novo autoimmune hepatitis after liver transplantation in children.
Pediatric transplantation - 1 Aug 2012
Hadžić Nedim, Quaglia Alberto, Cotoi Corina, Hussain Munther J, Brown Nigel, Vergani Diego, Mieli-Vergani Giorgina
Abstract excerpt
We have investigated the inflammatory infiltrate in post-transplant dn-AIH, a form of late insidious graft rejection, focusing on transcription factors defining effector and T-regs, using an antigen retrieval immunohistochemical method on archived liver tissue, and compared it with ACR and classical AIH. Paraffin-embedded liver biopsies from pediatric patients with dn-AIH (n = 10), ACR (n = 10), and AIH (n = 13)...
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