Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MET gain in diffuse astrocytomas is associated with poorer outcome.

Brain pathology (Zurich, Switzerland) - 1 Jan 2013

Pierscianek Daniela, Kim Young-Ho, Motomura Kazuya, Mittelbronn Michel, Paulus Werner, Brokinkel Benjamin, Keyvani Kathy, Wrede Karsten, Nakazato Yoichi, Tanaka Yuko, Mariani Luigi, Vital Anne, Sure Ulrich, Ohgaki Hiroko

Abstract excerpt

Glioblastoma may develop rapidly without evidence for precursor lesions (primary glioblastomas), or progress from diffuse or anaplastic astrocytomas (secondary glioblastomas). Despite having distinct genetic profiles, these glioblastoma subtypes have similar histological features. We hypothesized...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 7
Share to Astrocytoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Neoplasms

Share to Glioblastoma

Share to Isocitrate Dehydrogenase

Share to Oligodendroglioma

Share to Proto-Oncogene Proteins c-met

Share to Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 22672415
DOI: 10.1111/j.1750-3639.2012.00609.x
PMCID: PMC8028935

Genes

MET
IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22672415-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MET gain in diffuse astrocytomas is associated with poorer outcome.PMID 22672415Read ↗

Beyond IDH-Mutation: Emerging Molecular Diagnostic and Prognostic Features in Adult Diffuse GliomasSemantic proximity Read ↗

The definition of primary and secondary glioblastoma.Semantic proximity Read ↗

Extensive MET alterations confer clinical response to MET inhibitors in gliomasSemantic proximity Read ↗

National-level overall survival patterns for molecularly-defined diffuse glioma types in the United States.Semantic proximity Read ↗

Molecular Characterization of Astrocytoma Progression Towards Secondary Glioblastomas Utilizing Patient-Matched Tumor PairsSemantic proximity Read ↗

Adult-type Diffuse Gliomas.Semantic proximity Read ↗

Molecular Genetic Profile of 300 Japanese Patients with Diffuse Gliomas Using a Glioma-tailored Gene Panel.Semantic proximity Read ↗

Detection of IDH1 mutations in gliomatosis cerebri, but only in tumors with additional solid component: evidence for molecular subtypes.Semantic proximity Read ↗

Molecular signatures classify astrocytic gliomas by IDH1 mutation status.Semantic proximity Read ↗

Revisiting prognostic factors of gliomatosis cerebri in adult-type diffuse gliomas.Semantic proximity Read ↗

Genomic landscape of diffuse glioma revealed by whole genome sequencingSemantic proximity Read ↗

Genetic Alterations in Gliosarcoma and Giant Cell Glioblastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.