Article
Treatment of candidiasis: insights from host genetics.
Expert review of anti-infective therapy - 1 Aug 2012
Delsing Corine E, Bleeker-Rovers Chantal P, Kullberg Bart-Jan, Netea Mihai G
Abstract excerpt
Candida species are major causes of mucosal and invasive infections, leading to substantial morbidity and mortality. Despite the development of new classes of antifungal drugs, mortality in patients with systemic candidiasis remains high. Host-Candida interaction plays an important role in effective elimination of the pathogen. Genetic studies have rendered important insights into antifungal host defense and have...
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