Article
DNA damage down-regulates ΔNp63α and induces apoptosis independent of wild type p53.
Biochemical and biophysical research communications - 29 Jun 2012
Li Xiaorong, Chen Jing, Yi Yong, Li Chenghua, Zhang Yujun
Abstract excerpt
The tumor suppressor p53 is pivotal in cell growth arrest and apoptosis upon cellular stresses including DNA damage. Mounting evidence indicates that p63 proteins, which are homologs of p53, are also involved in apoptosis under certain circumstances. In this study, we found that treatment with DN...
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