Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population.

doi:10.1016/j.neulet.2012.05.062

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Article

Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population.

Neuroscience letters - 11 Jul 2012

Park Young Seok, Jeon Young Joo, Lee Bo Eun, Kim Tae Gon, Choi Joong-Uhn, Kim Dong-Seok, Kim Nam Keun

Abstract excerpt

Recent evidence has demonstrated associations between the single nucleotide polymorphism (SNP) rs11614913 in miR-196a2C>T and various pathologies. A main target of miRNA-196a is annexin A1 (lipocortin1, ANXA1), which is associated with increased multiple malignant tumors in brain models of ischemia and reperfusion injury. To determine the effects of miRNA SNPs in moyamoya disease, we recruited 107 patients with...

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PMID: 22659075
DOI: 10.1016/j.neulet.2012.05.062

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ANXA1

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