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[Analysis of association of genetic polymorphisms of microRNAs with ischemic stroke].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Apr 2017

Zhu Haogang, Zhang Hongjin, Bao Ligang, Dai Meifen

Abstract excerpt

OBJECTIVE: To assess the association of single nucleotide polymorphisms of hsa-miR-196a2, hsa-miR-149, hsa-miR-146a, hsa-miR-499 with susceptibility to ischemic stroke. METHODS: Taqman-PCR and DNA sequencing assays were employed to determine the genotypes of the 4 loci among 510 patients and 523 controls. And their association with the disease was assessed. RESULTS: Analysis showed that smoking, diabetes,...

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PMID: 28397233
DOI: 10.3760/cma.j.issn.1003-9406.2017.02.025

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