Article
Prevalence of hepatitis C virus variants resistant to NS3 protease inhibitors or the NS5A inhibitor (BMS-790052) in hepatitis patients with genotype 1b.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2012
Suzuki Fumitaka, Sezaki Hitomi, Akuta Norio, Suzuki Yoshiyuki, Seko Yuya, Kawamura Yusuke, Hosaka Tetsuya, Kobayashi Masahiro, Saito Satoshi, Arase Yasuji, Ikeda Kenji, Kobayashi Mariko, Mineta Rie, Watahiki Sachiyo, Miyakawa Yuzo, Kumada Hiromitsu
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) of genotype 1b is the most prevalent worldwide, and the least responsive to interferon-based treatments. A combination therapy with two direct-acting antivirals has shown promising results in patients with HCV-1b, but the prevalence of drug-resistant variants b...
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