Fevers, genes, and innate immunity.

Abstract excerpt

The characterization of patients with recurrent inflammatory syndromes into distinct clinical phenotypes provided early clues to the mode of inheritance of these conditions and facilitated the subsequent identification of causative gene mutations. The prototype autoinflammatory syndrome, familial Mediterranean fever, is characterized by self-limiting episodes of localized inflammation. Hallmarks of the classical...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Immunity, Innate
• Share to Mevalonate Kinase Deficiency
• Share to NLR Family, Pyrin Domain-Containing 3 Protein