Article
Missense polymorphisms within IL-10R1 exons are not associated with systemic lupus erythematosus in Chinese.
Lupus - 1 Oct 2012
Cui H, Xue H, Yang L, Liu D, Qi L, Zhang N
Abstract excerpt
OBJECTIVE: Studies have suggested that interleukin-10 receptor1 (IL-10R1) is involved in genetic susceptibility to systemic lupus erythematosus (SLE) in animal models and Caucasians. Therefore, the current study was designed to determine whether the IL-10R1 gene plays a role in the pathogenesis of human SLE in the Chinese Han population. METHODS: The seven exons of the IL-10R1 gene were amplified and sequenced...
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