Article
ANK3 and CACNA1C--missing genetic link for bipolar disorder and major depressive disorder in two German case-control samples.
Journal of psychiatric research - 1 Aug 2012
Kloiber Stefan, Czamara Darina, Karbalai Nazanin, Müller-Myhsok Bertram, Hennings Johannes, Holsboer Florian, Lucae Susanne
Abstract excerpt
Recent genome-wide association studies (GWAS) and metaanalyses revealed genetic associations for ANK3 (ankyrin 3) and CACNA1C (alpha 1C subunit of the L-type voltage gated calcium channel) with bipolar disorder (BPD). Several findings from clinical, epidemiological, and genetic studies point towards a common biological background of BPD and major depressive disorder (MDD). We were interested whether this also...
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