Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Forkhead Box Transcription Factor FOXC1 Promotes Breast Cancer Invasion by Inducing Matrix Metalloprotease 7 (MMP7) Expression

30 May 2012

Abstract excerpt

Therapeutic options for treatment of basal-like breast cancers are limited and identification of molecular targets for novel therapies to treat this aggressive cancer is urgently needed. Recently, FOXC1, a forkhead box transcription factor, was identified as a functionally important biomarker of breast cancer aggressiveness and the basal-like breast cancer subtype. However, the mechanism through which FOXC1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to FOXO transcription factor regulation
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22645147
DOI: 10.1074/jbc.m112.375865

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Forkhead Box Transcription Factor FOXC1 Promotes Breast Cancer Invasion by Inducing Matrix Metalloprotease 7 (MMP7) ExpressionPMID 22645147Read ↗

FOXC1, the new player in the cancer sandboxSemantic proximity Read ↗

Overexpression of CDCA7 predicts poor prognosis and induces EZH2‐mediated progression of triple‐negative breast cancerSemantic proximity Read ↗

The WISP1/Src/MIF Axis Promotes the Malignant Phenotype of Non-Invasive MCF7 Breast Cancer Cells.Semantic proximity Read ↗

Potential Tumor Suppressor Role for the c-Myb Oncogene in Luminal Breast CancerSemantic proximity Read ↗

Differential roles for membrane-bound and soluble syndecan-1 (CD138) in breast cancer progression.Semantic proximity Read ↗

FOXF2 suppresses the FOXC2-mediated epithelial-mesenchymal transition and multidrug resistance of basal-like breast cancer.Semantic proximity Read ↗

E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell MigrationSemantic proximity Read ↗

The WISP1/Src/MIF Axis Promotes the Malignant Phenotype of Non-Invasive Breast Cancer CellsSemantic proximity Read ↗

E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell MigrationSemantic proximity Read ↗

FOXA1 represses the molecular phenotype of basal breast cancer cells.Semantic proximity Read ↗

Moesin expression is a marker of basal breast carcinomasSemantic proximity Read ↗

NFAT promotes carcinoma invasive migration through glypican-6Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.