Article
Glutathione S-transferase Pi expression predicts response to adjuvant chemotherapy for stage C colon cancer: a matched historical control study.
BMC cancer - 28 May 2012
Jankova Lucy, Robertson Graham, Chan Charles, Tan King L, Kohonen-Corish Maija, Fung Caroline L-S, Clarke Candice, Lin Betty P C, Molloy Mark, Chapuis Pierre H, Bokey Les, Dent Owen F, Clarke Stephen J
Abstract excerpt
BACKGROUND: This study examined the association between overall survival and Glutathione S-transferase Pi (GST Pi) expression and genetic polymorphism in stage C colon cancer patients after resection alone versus resection plus 5-fluourouracil-based adjuvant chemotherapy. METHODS: Patients were drawn from a hospital registry of colorectal cancer resections. Those receiving chemotherapy after it was introduced in...
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