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Article

C9ORF72 repeat expansion in amyotrophic lateral sclerosis in the Kii peninsula of Japan.

Archives of neurology - 1 Sept 2012

Ishiura Hiroyuki, Takahashi Yuji, Mitsui Jun, Yoshida Sohei, Kihira Tameko, Kokubo Yasumasa, Kuzuhara Shigeki, Ranum Laura P W, Tamaoki Tomoko, Ichikawa Yaeko, Date Hidetoshi, Goto Jun, Tsuji Shoji

Abstract excerpt

BACKGROUND: In the Kii peninsula of Japan, high prevalences of amyotrophic lateral sclerosis (ALS) and parkinsonism-dementia complex have been reported. There are 2 major foci with a high prevalence, which include the southernmost region neighboring the Koza River (Kozagawa and Kushimoto towns in Wakayama prefecture) and the Hohara district (Mie prefecture). OBJECTIVE: To delineate the molecular basis of ALS in...

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PMID: 22637429
DOI: 10.1001/archneurol.2012.1219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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