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Identification of C9orf72 repeat expansions in patients with amyotrophic lateral sclerosis and frontotemporal dementia in mainland China.

Neurobiology of aging - 1 Apr 2014

Jiao Bin, Tang Beisha, Liu Xiaoyan, Yan Xinxiang, Zhou Lin, Yang Yi, Wang Junling, Xia Kun, Shen Lu

Abstract excerpt

The GGGGCC repeat expansion in the C9orf72 gene was recently identified as a major cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in white populations. To estimate the frequency of hexanucleotide repeats in patients with ALS and FTD from mainland China, we screened for C9orf72 in a cohort of 128 patients and 150 control subjects using the repeat-primed polymerase chain reaction...

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PMID: 24269022
DOI: 10.1016/j.neurobiolaging.2013.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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