Article
Genetic epidemiology of C9orf72 repeat expansion associated amyotrophic lateral sclerosis in Hungary.
Molecular medicine (Cambridge, Mass.) - 15 Apr 2026
Nagy Zsófia Flóra, Géresi Adrienn, Grosz Zoltán, Trombitás Barbara, Pál Margit, Nagy Dominika, Salamon András, Balicza Péter, Dézsi Lívia, Klivényi Péter, Széll Márta, Molnár Mária Judit
Abstract excerpt
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive motor neuron loss. The most common genetic cause of ALS is the hexanucleotide repeat expansion in the C9orf72 gene, which is associated with earlier disease onset, faster progression, and an increased frequency of cognitive and psychiatric involvement. Data on population-specific characteristics of...
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