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Article

Large C9orf72 repeat expansions are seen in Chinese patients with sporadic amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Feb 2016

Chen Yongping, Lin Ziqiang, Chen Xueping, Cao Bei, Wei Qianqian, Ou Ruwei, Zhao Bi, Song Wei, Wu Ying, Shang Hui-Fang

Abstract excerpt

An intronic GGGGCC hexanucleotide repeat expansion in the chromosome 9 open reading frame 72 (C9orf72) gene was considered as the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia in Caucasian populations. Using repeat-primed polymerase chain reaction analysis and Southern blotting methods, we assessed the frequency and size of hexanucleotide repeat expansion in a cohort of 918...

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Identifiers

PMID: 26725464
DOI: 10.1016/j.neurobiolaging.2015.11.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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