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Article

Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.

PloS one - 1 Jan 2012

Berry Diane J, Vimaleswaran Karani S, Whittaker John C, Hingorani Aroon D, Hyppönen Elina

Abstract excerpt

BACKGROUND: Mendelian randomization (MR) studies use genetic variants mimicking the influence of a modifiable exposure to assess and quantify a causal association with an outcome, with an aim to avoid problems with confounding and reverse causality affecting other types of observational studies. AIM: We evaluated genetic markers that index differences in 25-hydroxyvitamin D (25(OH)D) as instruments for MR studies...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22629401
DOI: 10.1371/journal.pone.0037465
PMCID: PMC3357436

Genes

OCA2
DHCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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