Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vitamin D genetic polymorphisms, adiposity, and hormonal response to a precision supplementation and genotype-guided diet intervention.

Nutricion hospitalaria - 16 Jun 2026

Stroia Carmina Mariana, Marian Florinda Petrinela, Vrânceanu Maria, Pallag Annamaria, Ghitea Timea Claudia

Abstract excerpt

Introduction: Background: vitamin D deficiency is highly prevalent in individuals with overweight or obesity, due to volumetric dilution and impaired metabolic activation. Genetic polymorphisms in VDR, CYP2R1, and GC genes may further influence serum 25-hydroxyvitamin D [25(OH)D] levels and responsiveness to supplementation. Objective: this study evaluated the longitudinal response to a 6-month, genotype-informed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adiposity
Share to Cholestanetriol 26-Monooxygenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P450 Family 2

Share to Dietary Supplements

Share to Parathyroid Hormone

Share to Vitamin D

Share to Vitamin D-Binding Protein

Share to Vitamin D Deficiency

Source

Identifiers

PMID: 41503852
DOI: 10.20960/nh.06050

Genes

CYP2R1
GC
CRP
PTH
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vitamin D genetic polymorphisms, adiposity, and hormonal response to a precision supplementation and genotype-guided diet intervention.PMID 41503852Read ↗

The Association of VDR, CYP2R1, and GC Gene Polymorphisms, Dietary Intake, and BMI in Regulating Vitamin D StatusSemantic proximity Read ↗

Genetic Variants Influencing Individual Vitamin D StatusSemantic proximity Read ↗

A genetic variant in the cytochrome P450 family 2 subfamily R member 1 determines response to vitamin D supplementation.Semantic proximity Read ↗

The Role of Polymorphisms in Vitamin D-Related Genes in Response to Vitamin D Supplementation.Semantic proximity Read ↗

Genetic variants in CYP2R1, CYP24A1, and VDR modify the efficacy of vitamin D3 supplementation for increasing serum 25-hydroxyvitamin D levels in a randomized controlled trial.Semantic proximity Read ↗

The GC2 haplotype of the vitamin D binding protein is a risk factor for a low plasma 25-hydroxyvitamin D concentration in a Han Chinese populationSemantic proximity Read ↗

Association of serum 25-hydroxyvitamin D with metabolic syndrome and type 2 diabetes: a one sample Mendelian randomization study.Semantic proximity Read ↗

CYP2R1 polymorphisms are important modulators of circulating 25-hydroxyvitamin D levels in elderly females with vitamin insufficiency, but not of the response to vitamin D supplementation.Semantic proximity Read ↗

Vitamin D-associated genetic variants in the Brazilian population: Investigating potential instruments for Mendelian randomization.Semantic proximity Read ↗

Common genetic determinants of vitamin D insufficiency: a genome-wide association study.Semantic proximity Read ↗

Vitamin D metabolism-related genetic variants, dietary protein intake and improvement of insulin resistance in a 2 year weight-loss trial: POUNDS Lost.Semantic proximity Read ↗

Genetic Variation in CYP2R1 and GC Genes Associated With Vitamin D Deficiency Status.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.