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Article

Circulating Serum 25-Hydroxyvitamin D Levels and Bone Mineral Density: Mendelian Randomization Study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 May 2018

Larsson Susanna C, Melhus Håkan, Michaëlsson Karl

Abstract excerpt

There is considerable discussion of the importance for increased serum 25-hydroxyvitamin D (S-25OHD) concentration associated with adequacy for bone health. Accordingly, whether long-term high S-25OHD concentration in general positively affects bone mineral density (BMD) is uncertain. We used a Mendelian randomization design to determine the association between genetically increased S-25OHD concentrations and...

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PMID: 29338102
DOI: 10.1002/jbmr.3389

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