Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population.

doi:10.1186/1471-2261-14-6

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Article

Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population.

BMC cardiovascular disorders - 14 Jan 2014

Zhao Chenxi, Ikeda Shinobu, Arai Tomio, Naka-Mieno Makiko, Sato Noriko, Muramatsu Masaaki, Sawabe Motoji

Abstract excerpt

BACKGROUND: The Ryanodine receptor 3 gene (RYR3) encodes an intracellular calcium channel that mediates the efflux of Ca2+ from intracellular stores. Two single-nucleotide polymorphisms (SNPs) in the RYR3 gene have been shown to associate with stroke (rs877087) and carotid intima-media thickness (rs2229116) in two independent genome-wide association studies (GWAS) in Caucasian. We investigated the effect of these...

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PMID: 24423397
DOI: 10.1186/1471-2261-14-6
PMCID: PMC3898238

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RYR3

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