Article
Drosophila apc regulates delamination of invasive epithelial clusters.
Developmental biology - 1 Aug 2012
De Graeve F M, Van de Bor V, Ghiglione C, Cerezo D, Jouandin P, Ueda R, Shashidhara L S, Noselli S
Abstract excerpt
Border Cells in the Drosophila ovaries are a useful genetic model for understanding the molecular events underlying epithelial cell motility. During stage 9 of egg chamber development they detach from neighboring stretched cells and migrate between the nurse cells to reach the oocyte. RNAi screening allowed us to identify the dapc1 gene as being critical in this process. Clonal and live analysis showed a...
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