Article
Novel spatiotemporal patterns of epithelial tumor invasion in Drosophila discs large egg chambers.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2005
Goode Scott, Wei Jun, Kishore Sirish
Abstract excerpt
Loss of Discslarge (Dlg) in early Drosophila egg chambers causes invasion of tumor follicle cells from the anterior epithelium, a pattern that resembles developmental border cell migration during mid-oogenesis. Here, we have analyzed novel spatial and temporal patterns of dlg invasion. Even though Dlg is ubiquitously expressed in all follicle cells, invasions are biased at the anterior and posterior termini. The...
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