Genetic and mechanistic evaluation for the mixed-field agglutination in B3 blood type with IVS3+5G>A ABO gene mutation.

doi:10.1371/journal.pone.0037272

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Article

Genetic and mechanistic evaluation for the mixed-field agglutination in B3 blood type with IVS3+5G>A ABO gene mutation.

PloS one - 1 Jan 2012

Chen Ding-Ping, Tseng Ching-Ping, Wang Wei-Ting, Sun Chien-Feng

Abstract excerpt

BACKGROUND: The ABO blood type B(3) is the most common B subtype in the Chinese population with a frequency of 1/900. Although IVS3+5G>A (rs55852701) mutation of B gene has been shown to associate with the development of B(3) blood type, genetic and mechanistic evaluation for the unique mixed-field agglutination phenotype has not yet been completely addressed. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we...

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PMID: 22624005
DOI: 10.1371/journal.pone.0037272
PMCID: PMC3356269

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