Meta-analysis of association between the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 gene and diabetic retinopathy in Caucasians and Asians.

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Meta-analysis of association between the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 gene and diabetic retinopathy in Caucasians and Asians.

Molecular vision - 1 Jan 2012

Ma Jinlan, Li Yan, Zhou Fang, Xu Xiaoyi, Guo Gang, Qu Yi

Abstract excerpt

PURPOSE: The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 (PPARγ2) gene is reported to be associated with diabetes. However, the gene's association with diabetic retinopathy (DR) in type 2 diabetes mellitus (T2DM) has been investigated in numerous epidemiologic studies with controversial results. This meta-analysis aimed to collectively assess the association of the Pro12Ala...

Topics

Aged
Alleles
Asia
Asian People
Databases, Bibliographic
Diabetes Mellitus, Type 2
Diabetic Retinopathy
Europe
Female
Genetic Predisposition to Disease
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Middle Aged

Odds Ratio

PPAR gamma

Polymorphism, Single Nucleotide

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 22993484
PMCID: PMC3444298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Meta-analysis of association between the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 gene and diabetic retinopathy in Caucasians and Asians.PMID 22993484Read ↗

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Association of Pro12Ala polymorphism in peroxisome proliferator activated receptor gamma with proliferative diabetic retinopathy.Semantic proximity Read ↗

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