The human carotid body transcriptome with focus on oxygen sensing and inflammation – a comparative analysis

Abstract excerpt

Key points The carotid body (CB) is the key oxygen sensor and governs the ventilatory response to hypoxia. CB oxygen sensing and signalling gene expression is well described in animals whereas human data are absent. Here we have characterized the human CB global gene expression in comparison with functionally related tissues and mouse CB gene expression. We show that the human CB expresses oxygen sensing genes in...

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