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Article

Lentiviral expression of anti-microRNAs targeting miR-27a inhibits proliferation and invasiveness of U87 glioma cells.

Molecular medicine reports - 1 Aug 2012

Feng Su Y, Dong Chang G, Wu William K K, Wang Xiao J, Qiao Jian, Shao Jun F

Abstract excerpt

Glioma is a highly fatal malignant disease and its treatment options are limited. microRNAs represent a novel target for the treatment of cancer. In the present study, we used a lentiviral vector to stably express anti-microRNAs targeting the oncogenic miR-27a in U87 glioma cells. The stable expression of anti-miR-27a significantly reduced the proliferation and increased the accumulation of U87 cells in the...

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Identifiers

PMID: 22614734
DOI: 10.3892/mmr.2012.915
PMCID: PMC3493108

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CCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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