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Anti-miRNA-23a Oligonucleotide Suppresses Glioma Cells Growth by Targeting Apoptotic Protease Activating Factor-1

14 Aug 2013

Abstract excerpt

BACKGROUND: Abnormal expression of microRNAs (miRNAs) is closely related to glioma, which is one of the most common malignant brain tumors. The current study is to identify the key miRNAs involved in the pathogenesis of glioma and to discover novel therapeutic targets for this disease. MATERIALS AND METHODS: Total RNA was extracted from glioma tissues of 100 patients. The microRNA microarray and the northern blot...

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PMID: 23865473
DOI: 10.2174/13816128113199990509

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