Article
[Genotype and phenotype polymorphisms of NAT2 and CYP2E1 in the Han Chinese pediatric population].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 1 May 2012
Liu Fang, Miao Qing, Jiao Wei-Wei, Xiao Jing, Sun Lin, Shen Chen, Wu Xi-Rong, Shen Dan, Yin Qing-Qin, Shen A-Dong
Abstract excerpt
OBJECTIVE: N-acetyltransferase 2 (NAT2) and cytochrome P450 2EI (CYP2E1) play a crucial role in the drug metabolic process. The aim of this study was to understand the genotype and phenotype polymorphisms of NAT2 and CYP2E1 in the Han Chinese pediatric population in order to provide a theoretical basis for individualized drug treatment. METHODS: A total of 341 (211 males and 130 females) randomly sampled Han...
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