Article
Genetical factors--other than HLA-B27--in "HLA-B27-associated diseases".
Scandinavian journal of rheumatology. Supplement - 1 Jan 1990
Derhaag P J
Abstract excerpt
All studies among acute anterior uveitis (AAU) and ankylosing spondylitis (AS) agree on the importance of and high association with HLA-B27. However, the majority (greater than 95%) of the HLA-B27+ population will never develop such disease. There are two--generally accepted--important factors increasing the relative risk for developing AAU or AS. Firstly being HLA-B27 positive and secondly being a first degree...
Topics
- Acute Disease
- Chromosomes, Human, Pair 6
- Family
- Gene Frequency
- Genes, MHC Class I
- Genetic Predisposition to Disease
- HLA-B27 Antigen
- Haplotypes
- Humans
- Risk Factors
- Spondylitis, Ankylosing
