Article
An update on the genetics of HLA B27-associated acute anterior uveitis.
Ocular immunology and inflammation - 1 Apr 2011
Martin Tammy M, Rosenbaum James T
Abstract excerpt
The discovery of the association of HLA B27 with spondyloarthropathy led to more questions than answers about the role of this gene in disease susceptibility. The realization that HLA B27 was not responsible for all of the genetic effects helped to lay a foundation for further investigation into the genetics of uveitis. Over several decades, genetic findings have provided clues to advance the understanding of...
Topics
- Acute Disease
- Animals
- Chromosome Mapping
- Gene Dosage
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Global Health
- HLA-B27 Antigen
- Humans
- Major Histocompatibility Complex
- Spondylarthropathies
- Uveitis, Anterior