Article
Association of HLA-alleles with the immune regulation of chronic viral infections.
The international journal of biochemistry & cell biology - 1 Aug 2012
Elahi Shokrollah, Horton Helen
Abstract excerpt
Cytotoxic CD8 T lymphocytes (CTLs) have an astonishing ability to eliminate pathogen-infected cells. However, if uncontrolled, these CTLs could cause devastating pathology to host tissues. CD8(+) effector T cells, therefore, interact with antigen-presenting cells and other immune cells, such as r...
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