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Article

Ultradeep sequencing analysis of population dynamics of virus escape mutants in RNAi-mediated resistant plants.

Molecular biology and evolution - 1 Nov 2012

Martínez Fernando, Lafforgue Guillaume, Morelli Marco J, González-Candelas Fernando, Chua Nam-Hai, Daròs José-Antonio, Elena Santiago F

Abstract excerpt

Plant artificial micro-RNAs (amiRs) have been engineered to target viral genomes and induce their degradation. However, the exceptional evolutionary plasticity of RNA viruses threatens the durability of the resistance conferred by these amiRs. It has recently been shown that viral populations not experiencing strong selective pressure from an antiviral amiR may already contain enough genetic variability in the...

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Identifiers

PMID: 22593223
DOI: 10.1093/molbev/mss135
PMCID: PMC7187544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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