Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular evolution of a viral non-coding sequence under the selective pressure of amiRNA-mediated silencing.

PLoS pathogens - 1 Feb 2009

Lin Shih-Shun, Wu Hui-Wen, Elena Santiago F, Chen Kuan-Chun, Niu Qi-Wen, Yeh Shyi-Dong, Chen Chin-Chih, Chua Nam-Hai

Abstract excerpt

Plant microRNAs (miRNA) guide cleavage of target mRNAs by DICER-like proteins, thereby reducing mRNA abundance. Native precursor miRNAs can be redesigned to target RNAs of interest, and one application of such artificial microRNA (amiRNA) technology is to generate plants resistant to pathogenic viruses. Transgenic Arabidopsis plants expressing amiRNAs designed to target the genome of two unrelated viruses were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Chi-Square Distribution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Innate

Share to MicroRNAs

Share to Mosaic Viruses

Share to Nicotiana

Share to Plant Diseases

Share to Plants, Genetically Modified

Source

Open in PubMed Open full text

Identifiers

PMID: 19247440
DOI: 10.1371/journal.ppat.1000312
PMCID: PMC2642722

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular evolution of a viral non-coding sequence under the selective pressure of amiRNA-mediated silencing.PMID 19247440Read ↗

Tempo and mode of plant RNA virus escape from RNA interference-mediated resistance.Semantic proximity Read ↗

Ultradeep sequencing analysis of population dynamics of virus escape mutants in RNAi-mediated resistant plants.Semantic proximity Read ↗

Highly specific gene silencing by artificial microRNAs in Arabidopsis.Semantic proximity Read ↗

Mutations in virus-derived small RNAs.Semantic proximity Read ↗

Transcriptomic insights into the epigenetic modulation of turnip mosaic virus evolution in Arabidopsis thaliana.Semantic proximity Read ↗

ADAR1 Biology Can Hinder Effective Antiviral RNA Interference.Semantic proximity Read ↗

The rate and character of spontaneous mutation in an RNA virus.Semantic proximity Read ↗

Differential expression of novel microRNAs in response to the infection of a TMV mutant with an internal poly(A) tract in N. benthamiana.Semantic proximity Read ↗

Genetic analyses of the FRNK motif function of Turnip mosaic virus uncover multiple and potentially interactive pathways of cross-protection.Semantic proximity Read ↗

Mutations in Turnip mosaic virus genomes that have adapted to Raphanus sativus.Semantic proximity Read ↗

Stable and unstable mutations in the 5' non-translated regions of tomato aspermy virus RNAs 1 and 2 generated de novo from infectious cDNA clones containing a cauliflower mosaic virus 35S promoter.Semantic proximity Read ↗

The rate and spectrum of spontaneous mutations in a plant RNA virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.