Article
Tempo and mode of plant RNA virus escape from RNA interference-mediated resistance.
Journal of virology - 1 Oct 2011
Lafforgue Guillaume, Martínez Fernando, Sardanyés Josep, de la Iglesia Francisca, Niu Qi-Wen, Lin Shih-Shun, Solé Ricard V, Chua Nam-Hai, Daròs José-Antonio, Elena Santiago F
Abstract excerpt
A biotechnological application of artificial microRNAs (amiRs) is the generation of plants that are resistant to virus infection. This resistance has proven to be highly effective and sequence specific. However, before these transgenic plants can be deployed in the field, it is important to evaluate the likelihood of the emergence of resistance-breaking mutants. Two issues are of particular interest: (i) whether...
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