Article
Systemic analyses of immunophenotypes of peripheral T cells in non-segmental vitiligo: implication of defective natural killer T cells.
Pigment cell & melanoma research - 1 Sept 2012
Zhou Li, Li Kai, Shi Yu-Ling, Hamzavi Iltefat, Gao Tian-Wen, Henderson Marsha, Huggins Richard H, Agbai Oma, Mahmoud Bassel, Mi Xiaofan, Lim Henry W, Mi Qing-Sheng
Abstract excerpt
Although it is widely believed that non-segmental vitiligo (NSV) results from the autoimmune destruction of melanocytes, a clear understanding of defects in immune tolerance, which mediate this uncontrolled self-reactivity, is still lacking. In the present study, we systemically evaluated circulating regulatory T (Treg) cells, including CD4(+) CD25(+) FoxP3(+) Treg cells and invariant natural killer T (iNKT)...
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