Article
Association of GZMB polymorphisms and susceptibility to non-segmental vitiligo in a Korean population.
Scientific reports - 11 Jan 2021
Jeong Ki-Heon, Kim Su Kang, Seo Jong-Kil, Shin Min Kyung, Lee Mu-Hyoung
Abstract excerpt
Non-segmental vitiligo (NSV) is the most common type of vitiligo, which is characterized by chronic and progressive loss of melanocytes. Genetic factors have been shown to play a key role in NSV in association and family studies. Granzyme B is a serine protease found in the cytoplasmic granules of cytotoxic T lymphocytes and natural killer cells that play an important role in inducing apoptotic changes of target...
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