Article
A single nucleotide polymorphism within the novel sex-linked testis-specific retrotransposed PGAM4 gene influences human male fertility.
PloS one - 1 Jan 2012
Okuda Hidenobu, Tsujimura Akira, Irie Shinji, Yamamoto Keisuke, Fukuhara Shinichiro, Matsuoka Yasuhiro, Takao Tetsuya, Miyagawa Yasushi, Nonomura Norio, Wada Morimasa, Tanaka Hiromitsu
Abstract excerpt
BACKGROUND: The development of novel fertilization treatments, including in vitro fertilization and intracytoplasmic injection, has made pregnancy possible regardless of the level of activity of the spermatozoa; however, the etiology of male-factor infertility is poorly understood. Multiple studies, primarily through the use of transgenic animals, have contributed to a list of candidate genes that may affect male...
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