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Article

Dissection of complex adult traits in a mouse synthetic population.

Genome research - 1 Aug 2012

Burke David T, Kozloff Kenneth M, Chen Shu, West Joshua L, Wilkowski Jodi M, Goldstein Steven A, Miller Richard A, Galecki Andrzej T

Abstract excerpt

Finding the causative genetic variations that underlie complex adult traits is a significant experimental challenge. The unbiased search strategy of genome-wide association (GWAS) has been used extensively in recent human population studies. These efforts, however, typically find only a minor fraction of the genetic loci that are predicted to affect variation. As an experimental model for the analysis of adult...

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Identifiers

PMID: 22588897
DOI: 10.1101/gr.135582.111
PMCID: PMC3409268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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