Article
Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo.
Infection and immunity - 1 Aug 2012
van Gennip Maria, Christensen Louise Dahl, Alhede Morten, Qvortrup Klaus, Jensen Peter Østrup, Høiby Niels, Givskov Michael, Bjarnsholt Thomas
Abstract excerpt
Chronic infections with Pseudomonas aeruginosa persist because the bacterium forms biofilms that are tolerant to antibiotic treatment and the host immune response. Scanning electron microscopy and confocal laser scanning microscopy were used to visualize biofilm development in vivo following intraperitoneal inoculation of mice with bacteria growing on hollow silicone tubes, as well as to examine the interaction...
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